Scientist I, Protein Science

Company: Modex Therapeutics Ltd.
Location: Weston
Posted on: March 5, 2026

Job Description:

Company Overview ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary-multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com . Job Description We are seeking an experienced and highly motivated biochemist to join our Protein Science group. The individual will be a key member of the protein production and analytics team tasked with design, production and functional characterization efforts for our therapeutic programs. This role requires strong technical expertise, scientific independence, and the ability to translate complex data into clear conclusions that guide therapeutic lead selection and optimization. This is an exciting opportunity to be part of a cross-functional team and contribute to the development of cutting-edge biotherapeutics in a fast-paced, rapidly growing biotech company with a bold vision. Key responsibilities include but are not limited to: Collaborate closely with cross-function teams, drive the design, expression and purification of innovative multispecific antibodies and other therapeutic molecules. Lead the in vitro functional screening and analytical characterization of multispecific antibodies and therapeutic proteins to support therapeutic lead identification and optimization. Develop and optimize high throughput protein production and characterization methods and contribute to our antibody developability screening platforms for the generation of robust, decision-enabling data. Drive experimental strategy, execution, troubleshooting, data analysis, and communication with cross-functional teams. Ensure effective, high-quality and timely documentation in electronic laboratory notebooks. Qualifications: Degree required: BS or MS in protein science, biochemistry, analytical chemistry or other related disciplines Lab experience required: BS with 6 or MS with 3 years of relevant experience, preferably in biotech and biopharmaceutical industry. Strong knowledge and hands-on experience in common antibody expression platforms and purification methods. Proficiency with AKTA and the ability to develop multistep chromatography-based purification methods are required. Knowledge in methods for characterizing protein-protein interactions using SPR, BLI and ELISA to assess binding affinity, kinetics, and potency. Familiar with various protein analytics platforms such as HPLC, UPLC, DLS/SLS, and related biophysical methods for protein purity and stability assessment. Solid understanding of antibody structure, function, and biologics drug discovery and development workflows. Demonstrated ability to work independently and lead projects with minimal supervision. Attention to details, outstanding troubleshooting and problem-solving skills. Excellent written and oral communication, organization, and data interpretation skills. Highly adaptable to a fast-paced work environment and capable of working both independently and collaboratively within project teams. ModeX Therapeutics is an Equal Opportunity Employer

Keywords: Modex Therapeutics Ltd., Lawrence , Scientist I, Protein Science, Science, Research & Development , Weston, Massachusetts